| 22/09 | Setubal VS Portimonense | 0:0 | X FT |
|---|---|---|---|
| 22/09 | Bor. Freialdenhoven VS FC Pesch | 3:2 | OVER 2.5 |
| 22/09 | Fylkir FC VS Stjarnan FC | 1:4 | OVER 2.5 |
| 22/09 | Rudar Velenje VS NK Domzale | 2:3 | GG or OVER 2.5 |
| 22/09 | ND Triglav VS NK Maribor | 1:3 | OVER 2.5 |
| 22/09 | FC Vorskla Poltava VS FC Dynamo Kiev | 0:5 | 2 |
| 22/09 | SFC Desna Chernihiv VS FC Shakhtar Donetsk | 0:1 | 2 |
| 22/09 | IF Elfsborg VS Malmo FF | 0:3 | AWEH |
| 22/09 | Hammarby IF VS AIK | 2:1 | BTTS / GG |
| 22/09 | BSC Young Boys VS FC Basel | 1:1 | BTTS / GG |
| 22/09 | Esbjerg VS Brondby | 3:1 | BTTS / GG |
| 22/09 | Ludogorets Razgrad VS FK Arda Kurdzhali | 2:0 | 1 |
| 22/09 | LASK Linz VS FC Salzburg | 2:2 | OVER 1.5 |
| 22/09 | St Johnstone VS Rangers | 0:4 | 2 |
| 22/09 | Celtic VS Kilmarnock | 3:1 | 1 |
| 22/09 | FC Porto VS CD Santa Clara | 2:0 | 1 |
| 22/09 | Eintracht Frankfurt VS Borussia Dortmund | 2:2 | GG or OVER 2.5 |
| 22/09 | Monchengladbach VS Fortuna Dusseldorf | 2:2 | OVER 1.5 |
| 22/09 | Lazio VS Parma | 2:0 | 1 |
| 22/09 | Lecce VS Napoli | 1:4 | 2 |
